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Highlights Jul 27 - Aug 2, 2026

new every Sunday

This week brought an early clinical signal for psilocybin-assisted therapy in veterans with severe PTSD, alongside studies refining how psychedelics affect brain networks and stress biology. Practical harm reduction and scrutiny of underground care rounded out the picture.

  1. 01 Safety, feasibility, and preliminary clinical outcomes of psilocybin-assisted therapy for veterans with severe, treatment-resistant PTSD: an open-label pilot clinical trial - Communications Medicine

    A pilot in veterans found psilocybin therapy was well tolerated and reduced severe PTSD symptoms, though the study lacked a control group.

    nature.com · Jul 30, 2026 Unspecified Research
  2. 02 Neuroscientists find psychedelics may alter brain function through shifts in cortical hierarchy, challenging the idea that stronger global connectivity explains the psychedelic state

    Cross-compound imaging links psychedelic states to a flatter cortical hierarchy, challenging stronger global connectivity as the main explanation.

    psypost.org · Jul 30, 2026 LSD Research
  3. 03 Meskalin veraendert Kleinhirn-Funktion und globale Hirnvernetzung - fMRT-Studie an Ratten zeigt Hinweise auf neuronale Mechanismen psychedelischer Wahrnehmungsveraenderungen

    Rat fMRI data link mescaline to cerebellar and whole-brain network changes, broadening models beyond primarily cortical effects.

    psychedelia-stiftung.de · Jul 30, 2026 Mescaline Research
  4. 04 Ayahuasca may protect the brain from stress-related damage in marmosets, with changes in neural plasticity markers linked to resilience and reduced inflammation

    In stressed marmosets, ayahuasca was associated with lower inflammation and altered plasticity markers, but human benefit remains untested.

    psypost.org · Aug 2, 2026 Ayahuasca Research
  5. 05 Know Before You Go gives festivalgoers practical harm reduction guidance on substance checking, hydration, consent, overheating, and emergency response before events

    Festival guidance turns substance checking, hydration, overheating, consent, and emergency response into practical steps before an event.

    hali.foundation · Jul 31, 2026 Unspecified HarmReduction
  6. 06 Underground psychedelic guides face ethical and practical questions about disclosure, training, consent, and the risks of operating outside legal therapeutic systems

    Underground guides face unresolved questions about training, disclosure, consent, boundaries, and accountability outside licensed systems.

    ecstaticintegration.org · Jul 28, 2026 Unspecified Ethics