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Psilocybin

Psilocybin content spanning clinical trials, mushroom science, public policy, and community discussion around one of the core substances in the psychedelic resurgence.

Most recent Latest added

Most recent Latest added

391 entries

July 3, 2026

A single dose of psilocybin reduces reward-seeking behavior by altering inhibitory brain cells in the prefrontal cortex, with effects linked to SST interneurons

psypost.org · Jul 3, 2026 · Eric W. Dolan

Psilocybin Article Clinical Consciousness Research

July 2, 2026

Psilocybin improves sleep quality in patients with chronic cluster headaches, with better rest linked to lower attack burden and broader quality-of-life gains

psypost.org · Jul 2, 2026 · Eric W. Dolan

Psilocybin Clinical Research Therapy

July 1, 2026

Psilocybin could help repair chemotherapy-related peripheral nerve damage by promoting neurite growth, reducing inflammation, and easing neuropathic pain

thesporereport.com · Jul 1, 2026 · admin

Psilocybin Article Clinical Research Therapy

Veterans and psychedelics event at RAND examines policy, clinical evidence, and implementation challenges for psychedelic-assisted care in military and veteran settings

rand.org · Jul 1, 2026

Psilocybin MDMA Clinical Policy Therapy

June 28, 2026

LSD for depression shows mixed Phase 3 results as Definium's data highlights remission gains, weaker response rates, and unresolved comparisons with psilocybin

thesporereport.com · Jun 28, 2026 · admin

LSD Psilocybin Article Clinical +2

An international brain imaging analysis finds psychedelics reorganize cortical connectivity, increasing global integration while reducing localized network segregation

psypost.org · Jun 28, 2026 · Karina Petrova

LSD Psilocybin Clinical Consciousness +2

June 26, 2026

Psilocybin was linked to regained speech, mobility, and engagement in an 80-year-old woman with advanced Alzheimer's in a single caregiver-reported case

psypost.org · Jun 26, 2026 · Eric W. Dolan

Psilocybin Article Clinical Research Therapy

June 23, 2026

Psilocybin addiction recovery research links immune system inflammation shifts, not brain biomarkers alone, to stronger treatment response and reduced substance use risk

thesporereport.com · Jun 23, 2026 · admin

Psilocybin Clinical Research Therapy

June 14, 2026

Psilocybin restores cognitive function and synaptic density in an Alzheimer's mouse model, with stronger gains after low-dose treatment before plaque onset

neurosciencenews.com · Jun 14, 2026 · Neuroscience News

Psilocybin Article Clinical Research

A single dose of psilocybin shows months-long reductions in chronic suicidal ideation, with a small new study reporting durable effects and manageable acute risks

psypost.org · Jun 14, 2026 · Eric W. Dolan

Psilocybin Article Clinical Research Therapy

June 13, 2026

Psilocybin's anti-inflammatory and neuroplastic effects are being examined for whether they could help protect the aging brain and reduce dementia-related decline

thesporereport.com · Jun 13, 2026 · admin

Psilocybin Clinical Microdosing Research

June 10, 2026

The therapy requirement in the three most advanced psychedelic drug development programs shapes trial design, scalability, and eventual commercial adoption

cascades-analytics.com · Jun 10, 2026

Psilocybin MDMA Business Clinical Therapy

June 9, 2026

Largest real-world psychedelic study launches to track mental health, wellbeing, and outcomes across naturalistic use at unprecedented global scale

thesporereport.com · Jun 9, 2026 · admin

LSD Psilocybin Clinical Mainstream +5

Psilocybin use in a coma patient raises questions about consciousness, neuroplasticity, and the limits of psychedelic intervention in critical care

thesporereport.com · Jun 9, 2026 · admin

Psilocybin Article Clinical Consciousness Research

Chicago's VA hospital enrolls its first veterans in a psilocybin-assisted therapy program, expanding access to an experimental mental health treatment

medicaldaily.com · Jun 9, 2026

Psilocybin Article Clinical Research Therapy

June 8, 2026

Psychedelics are being investigated for neuroplasticity, inflammation, and mood effects that could help protect the aging brain and support healthier cognitive aging

news.berkeley.edu · Jun 8, 2026 · Kara Manke

LSD Psilocybin Clinical Research +3

Psilocybin therapy standardized for clinical depression shows large benefits in a randomized trial, with stronger effects than psychotherapy plus escitalopram

psypost.org · Jun 8, 2026 · Karina Petrova

Psilocybin Article Clinical Research Therapy

Scientists report that psilocybin microdoses may reverse obesity, fatty liver, and diabetes through cellular metabolic effects

thesporereport.com · Jun 8, 2026 · admin

Psilocybin Article Clinical Microdosing Research

June 6, 2026

Psilocybin may directly target Alzheimer’s disease mechanisms by reducing neuroinflammation, promoting neuroplasticity, and potentially slowing cognitive decline

thesporereport.com · Jun 6, 2026 · admin

Psilocybin Clinical Research

Psilocybin boosts gabapentin's pain-relieving effects in mice with nerve injury, pointing to a potential new approach for neuropathic pain treatment

psypost.org · Jun 6, 2026 · Eric W. Dolan

Psilocybin Article Clinical Research

June 5, 2026

High-dose magic mushrooms are linked to an Alzheimer's patient's regained speech and mobility in a case report that raises questions about psilocybin's neurological effects

dallasexpress.com · Jun 5, 2026 · Dallas Express

Psilocybin Clinical Research

Court overturns legal aid refusal in psilocybin post-trial case, allowing a patient to challenge denied access to continued treatment after a clinical study ended

psychedelics.co.uk · Jun 5, 2026

Psilocybin Article Clinical Policy Therapy

June 4, 2026

Psilocybin-assisted therapy shows durable depression relief in a major clinical trial, with stronger effects than placebo and growing implications for mental health care

thesporereport.com · Jun 4, 2026 · admin

Psilocybin Article Clinical Research Therapy

June 2, 2026

Psychedelics re-enter mainstream psychiatry at the American Psychiatric Association meeting amid clinical promise, professional caution, and tensions over evidence and implementation

psychedelicalpha.com · Jun 2, 2026

Psilocybin MDMA Article Clinical +3

May 30, 2026

Psilocybin affects men and women differently, with sex-linked differences in psychedelic intensity, side effects, and therapeutic response

thesporereport.com · May 30, 2026 · admin

Psilocybin Article Clinical Research Therapy