Brain receptor patterns separate sensory and cognitive networks

Brain receptor patterns are mapped to separate sensory and cognitive brain networks, helping explain how internal thoughts and emotions differ from signals driven by external influences. Researchers used a large macaque dataset of neurotransmitter receptor densities across more than 100 brain regions, applying in-vitro receptor autoradiography plus statistical and neuroimaging methods to link receptor organization with brain connectivity and anatomy. The openly available receptor maps are intended to bridge scales of neuroscience, support new computational brain models, and eventually help researchers target specific brain networks with medicines. The dataset is also positioned as a tool for studying differences seen in conditions such as schizophrenia and in people under substances like “magic mushrooms” (psilocybin).