Psychedelics improve mental health, cognition in special ops veterans: ibogaine plus 5-MeO-DMT chart review reports symptom reductions

Ibogaine hydrochloride plus 5-MeO-DMT therapy is linked to improved mental health and cognitive functioning in U.S. special operations forces veterans seeking care at a Mexico clinic. A chart-review analysis reported reductions in depression, anxiety, and PTSD symptoms, along with improvements in insomnia severity and anger from pre-treatment to one-month follow-up, with benefits extending through three and six months. Researchers also highlighted cognitive impairment related to traumatic brain injury as a notable area of improvement. The veterans received a single oral ibogaine hydrochloride dose and, on a separate day, incremental inhalation doses of 5-MeO-DMT totaling 50 mg, preceded and followed by preparation and reflection sessions. The work is positioned as supportive evidence for further testing of psychedelic-assisted therapies, including for complex trauma histories, particularly given limited response to traditional therapies for this population.