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Dr. Chandra Khalifian and Dr. Kayla Knopp: Enamory, Ketamine and Couples Therapy

Psychedelics Today · Feb 10, 2026
Open on psychedelicstoday.com
TL;DR

Enamory ketamine assisted couples therapy applies structured evidence based couples work while ketamine is used as a support tool to help partners access new perspective and emotional flexibility. Dr. Chandra Khalifian and Dr. Kayla Knopp connect their approach to their prior couples based PTSD research, describing couples therapy models that often stall when partners cannot soften, access vulnerability, or understand each other internal experiences. They also note earlier exposure to psychedelic assisted therapy research as informing how psychedelic states may temporarily reduce defensiveness and rigid narratives. The episode outlines how Enamory structures dosing and sessions, including models such as dual psychedelic dosing for shared perspective shifts, dual psycholytic dosing for gentler interaction, and individual sessions when relational patterns interfere with joint work. It emphasizes detailed assessment, integration sessions that translate insights into concrete relational change using couples therapy skills, and coordination with medical prescribers with clear scope of practice boundaries for therapists.

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Published Feb 10, 2026 · Added Mar 14, 2026