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Couples Are Turning to Ketamine-Assisted Therapy to Heal Their Relationships

Psychedelics Today · Feb 18, 2026 · Chandra E. Khalifian, PhD; Skylar Kelsven, PhD; Kayla C. Knopp, PhD
Open on psychedelicstoday.com
TL;DR

Ketamine-assisted couple therapy is presented as a structured way to help couples shift from rigid conflict cycles when traditional therapy has not produced change. The authors frame the current interest as part of a broader psychedelic resurgence, while noting that couples face modern stressors that can intensify avoidance, withdrawal, and emotional inaccessibility. They describe ketamine as potentially increasing perspective flexibility, emotional openness, and tolerance for difficult feelings, which may interrupt patterns like pursue-avoid or criticize-defend. They emphasize that couples receive preparation, medicine sessions, and integration, with the relationship itself treated as the client. The piece also highlights key clinical cautions, including contraindications, risks around bypassing ongoing relational work, and the need for specialized training and safe, ethical clinical containers. It states there is not yet couples-specific clinical trial evidence, but points to emerging clinical models and adaptation of evidence-based couple therapy interventions.

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Published Feb 18, 2026 · Added Mar 14, 2026