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5-meo DMT & meditation study results | Dr Christopher Timmermann

Reddit 5MeODMT · Dec 24, 2025 · Christopher Timmermann
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TL;DR

Scientific research into the intersection of advanced meditation and the psychedelic 5-MeO-DMT suggests a significant overlap between these two states of consciousness. An expert meditator from the Mahamudra tradition, characterized by over 17 years of practice, served as the primary subject for a controlled study involving both laboratory-based meditation sessions and administrations of 5-MeO-DMT. This investigation explored the shared neural mechanisms between these meditative and psychedelic states. Electroencephalography revealed that lower doses of 5-MeO-DMT yielded a high degree of similarity to the brain states observed during advanced meditation, specifically through the reduction of higher-frequency neural firing known as gamma power. This finding potentially identifies two distinct pathways to inducing states of pure awareness or non-duality-saturation via high-dose 5-MeO-DMT, and a subtractive route through meditation which actively reduces neural activity.

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Published Dec 24, 2025 · Added Mar 13, 2026