psychedelicstoday.com

The default mode network (DMN) is a key brain network linked to self-referential thought, mind-wandering, and the sense of an intact, ongoing self. Psychedelics are discussed in relation to how they may alter DMN activity and connectivity, which could help explain changes in ego boundaries, perception, and rumination during psychedelic experiences. The piece frames DMN modulation as one possible neurobiological mechanism behind psychedelic effects, connecting brain-network changes to altered cognition and consciousness states.