Dante Liberato ran 500 miles while microdosing LSD and psilocybin to study psychedelics impact on endurance, creating the documentary Dante

Psychedelics and endurance sports intersect through ultrarunner Dante Liberato, who ran 500 miles from Colorado Springs to Moab over 11 days while microdosing. Liberato took LSD and psilocybin during the run as part of an effort to understand how these substances affect human endurance and focus, with a film crew documenting his experience. He frames the goal as therapeutic learning rather than simple recreation, tying his interest to past mental health work and a therapist recommendation involving MDMA. The journey is portrayed as a trade-off: psychedelics sometimes boost focus and drive, but can also amplify fatigue, anxiety, and emotional volatility over long, multi-day efforts. As the run progressed, he adjusted his approach, using additional emotional regulation practices (like brief cathartic crying) when psychedelics were less helpful, and the full story feeds into the forthcoming documentary Dante.