Longevity enthusiast Bryan Johnson says smoking 5-MeO-DMT from Sonoran toad venom revealed the most expansive map of human consciousness

5-MeO-DMT from Sonoran toad venom is linked to Bryan Johnsons claim that it gave him an "expansive map" of human consciousness. Johnson, a longevity enthusiast, says he often wonders how big human consciousness is and looked to psychedelics to answer it. On the Core Memory podcast, Johnson frames the experience as more than insight into emotions. He argues that psychedelics revealed something broader about the mind and the possibility of pairing brain function with AI to explore consciousness. He contrasts the clarity from 5-MeO-DMT with alcohol and marijuana, says the experience was profound enough to tattoo the 5-MeO-DMT molecule on his body, and connects the discussion to his larger quest for understanding consciousness alongside his anti-aging regimen.