Psilocybin might not be the most psychoactive ingredient in magic mushrooms, new research suggests

Psilocybin might not be the main driver of magic mushroom psychoactivity, according to new research highlighted in the article. The findings suggest that other compounds in psilocybin-containing mushrooms could contribute to the overall subjective effects, potentially changing how potency is assessed beyond measuring psilocybin alone. The piece frames the result as relevant for research design and for safety and clinical expectations, since standard assumptions about which ingredients matter most can influence dosing, product labeling, and interpretation of study outcomes.