Sasha Shulgin & Terence McKenna in Prague (1992) | Prague Gnosis

Alexander Shulgin and Terence McKenna hold a conversation in a Jewish cemetery in Prague, focusing on the future of psychopharmacology and the potential societal impact of psychedelic compounds. They contrast the distinct effects of tryptamines with dissociatives like ketamine, while speculating on the discovery potential of new chemical classes. The discussion frames these substances as necessary tools for cognitive development in an increasingly complex and troubled world. They express frustration with current drug policies, characterizing them as deeply irrational and harmful to societal freedoms. The dialogue underscores a shared conviction that these substances, while misunderstood and stigmatized, possess an intrinsic significance for humanity that will eventually come to light.