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My Exhaustive Psychedelic Tier List 2023 | PsychedSubstance

Psyched Substance · Apr 8, 2023 · Psyched Substance
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TL;DR

Psychedelic substances including 20 common compounds are ranked on a tier list from S to D, evaluating their safety, potential for profound transpersonal experience, and physical side effects. This classification emphasizes that substances carry significant psychological risks despite some having no history of physical death via overdose. Education and harm reduction advice serve as essential components, focusing on the importance of preparation and setting to minimize danger. Each substance is viewed through the lens of individual biological response, acknowledging how body chemistry influences drug potency and the likelihood of negative physical or psychological outcomes, such as anxiety or dysphoria. The list highlights specific risks, such as the potential for bronchial constriction or the danger of misidentification in illicit markets, advocating for the use of testing reagents to ensure substance purity and safety during the psychedelic experience.

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Published Apr 8, 2023 · Added Mar 31, 2026