James Fadiman & Sophia Korb: Microdosing - The Phenomenon, Research Results & Startling Surprises

Microdosing consists of the consumption of small, non-psychedelic quantities of substances like LSD or psilocybin. Research into this practice, contrasted with traditional randomized controlled trials, reveals a complex, multi-variable human experience that is challenging to capture under strictly clinical conditions. Participants across diverse professional backgrounds report significant subjective benefits including improved sleep, enhanced focus, increased energy, and better emotional regulation. Some individuals also note a reduction in the use of other medications, including antidepressants, with anecdotal accounts suggesting improvements in conditions like treatment-resistant depression and migraines. Future research efforts are shifting toward analyzing these user-generated, anonymized reports as a valuable source of real-world data.