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Durability of Improvement in PTSD Symptoms After MDMA-Assisted Psychotherapy

MAPS · Feb 4, 2013 · Berra Yazar-Klosinski
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TL;DR

MDMA-assisted psychotherapy demonstrates sustainable mental health improvements for individuals suffering from chronic, treatment-resistant PTSD. Research indicates that the administration of MDMA in a controlled clinical setting, as an adjunct to talk therapy, helps patients process traumatic memories by decreasing fear and defensiveness while increasing empathy and interpersonal trust. Patients treated with this method showed significant reductions in PTSD severity that persisted long after the study finished. The therapeutic approach emphasizes creating a supportive set and setting, integrating breathing techniques, and fostering a deep, non-directive personal insight process, which allows participants to address the emotional and somatic components of their trauma.

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Published Feb 4, 2013 · Added Mar 31, 2026