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Treating PTSD with MDMA-Assisted Psychotherapy: 3D Motion Graphic

MAPS · Dec 17, 2012 · MAPS
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TL;DR

Post-traumatic stress disorder manifests as a debilitating condition characterized by persistent fear, avoidance, and hyper-arousal, often resulting in significant social and economic costs. Current research suggests it involves structural and functional shifts within the brain. MDMA-assisted psychotherapy functions by reducing amygdalar activity and promoting the release of hormones like oxytocin, which facilitates trust and emotional openness during therapeutic work. Clinical trials demonstrate strong efficacy, with 83% of participants no longer meeting the diagnostic criteria for PTSD post-treatment and sustaining these improvements years later.

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Published Dec 17, 2012 · Added Mar 31, 2026