Dr Michael Mithoefer - MDMA-assisted Psychotherapy for Treatment-Resistant Post-Traumatic Stress Dis
MDMA-assisted psychotherapy for chronic, treatment-resistant post-traumatic stress disorder is presented as a therapeutic approach centered on a non-directive, supportive environment. The methodology involves preparing patients through internal focus and alternating sessions with therapists during a drug-supported experience to help process traumatic emotions. Results from randomized, placebo-controlled trials indicate that MDMA significantly outperforms therapeutic support alone, with a notable reduction in Clinician Administered PTSD Scale (CAPS) scores maintained over time. Follow-up research and ongoing studies involving veterans and first responders suggest that integrating these sessions into a clinical setting can facilitate lasting relief for individuals with resistant trauma, emphasizing the necessity of preparation, integration, and safety in therapy.
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Published May 10, 2019 · Added Mar 31, 2026