Psychedelic Alpha Bulletin 222 covers meta-analysis on antidepressant effects, plus a first US patent application update

Meta-analysis evidence suggests psychedelics are not more effective than traditional antidepressants for depression. Psychedelic Alpha Bulletin 222 frames the finding as a clarification of comparative efficacy, placing psychedelic treatments alongside established antidepressant options rather than treating them as clearly superior. The bulletin also highlights industry momentum via the US first patent application publish, positioning psychedelics as continuing to move forward through formal intellectual property and commercialization pathways.