Pα+ Psychedelic Bulletin #181: Colorado rule changes and Cybin’s 12-month trial data amid controversy

Colorado’s state-regulated psychedelics rollout nears, and Pα+ reports last-minute rule changes that narrow where administrations can occur and create de facto opt-outs. Rule updates target “other locations” by limiting sessions outside healing centers to cases involving facilitators tied to licensed healing centers and participants requiring palliative care, undermining planned flexibility for independent facilitation. The bulletin also reviews Cybin’s 12-month data, arguing that results are weakened by small sample size while scrutiny grows over Cybin’s marketing messaging, alongside other policy and research items including DEA telemedicine extensions and discussion of neurobiology research framed around psychoactive-induced brain plasticity.