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Comparing psychedelic and meditation-related adverse events: parallels in symptoms, prevalence, mechanisms, and coping frameworks

Ecstatic Integration · Mar 24, 2026 · Jules Evans
Open on ecstaticintegration.org
TL;DR

Psychedelic-related adverse events and meditation-related adverse events show important parallels in symptoms, prevalence, and potential mechanisms. The post frames this comparison as an outgrowth of meditation adverse event research led by Willoughby Britton and related teams, and it links the presenter’s own Challenging Psychedelic Experiences Project to that precedent. It lists overlapping symptom categories such as increased anxiety, derealisation and depersonalisation, sleep issues, PTSD, and ontological shock, with a claim that adverse events may occur for up to around 40% of people in milder, short lived forms and around 8% in more disruptive, enduring ways. It also proposes a cognitive behavioral cycle after a triggering event: unexpected symptoms lead to catastrophising, hyper vigilant self monitoring, rumination, shame, withdrawal, and prolonged dysregulation. The post notes additional explanatory frameworks and cultural context, discusses therapy like CBT and acceptance and commitment approaches as potentially helpful, and highlights the need for better, better funded research into adverse events for both psychedelics and meditation.

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Published Mar 24, 2026 · Added Mar 24, 2026